Kevin N Dalby

Welcome to the homepage of Professor Kevin N Dalby at The University of Texas at Austin. The Dalby group investigates mechanisms of cancer cell signaling using chemical biology approaches

Title and Affiliation

Professor in Medicinal Chemistry, College of Pharmacy, The University of Texas at Austin

Co-director, Texas Screening Alliance for Cancer Therapeutics

Education and Training

1994-97    University of Dundee, Dundee, Scotland, medical research council postdoctoral fellow, biochemistry and cell biology

1992-94    Brandeis University, Waltham, Ma, USA, postdoctoral fellow, physical organic chemistry

1989-92    University of Cambridge, Cambridge, England, Ph.D., physical organic chemistry

1985-89    University of Leeds, Leeds, England, B.Sc. Hons (1st class), chemistry

Research Interests

A fundamental biochemical understanding of a protein provides a foundation from which to understand its cellular function.  We study the biochemical properties of proteins using a range of kinetic and thermodynamic techniques.  In select cases we identify small molecules or peptides that interfere with the biological functions of the proteins and investigate their mechanism of action in cellular model systems. These studies provide insight into cell signaling pathways and provide a basis for therapeutic development.  Our studies are enriched enormously through collaborations with structural biologists, pharmacologists, computer scientists and translational biologists.  Students with an interest in integrating the disciplines of chemistry, biochemistry, and cell biology to investigate mechanisms of cancer are strongly encouraged to apply.  If interested please e-mail Dr. Kevin Dalby

Dalby bio.pdf